Study Summary
 

PRISM

PRImary Care Streptococcal Management Study  (PRISM)  7/7/2006
 
Summary of the study
This study aims to find out which people with sore throat get better without problems, the few people who get worse or don’t get better quickly, and those who will benefit from antibiotics. In particular we want to find out whether throat swabs – which are used to detect bacterial infections - are a good way of targeting antibiotics.  Finding the answer to this important question will be the first step to better targeting antibiotics in the future to those who will benefit, help avoid side effects when antibiotics are not needed, and to reduce ‘resistance’ resulting from overuse of antibiotics.   

Up to 2100 patients presenting to their GP or practice nurse with a sore throat will have key clinical information collected by the GP or nurse – mainly by asking questions about how bad patient’s symptoms are, but also from a quick examination of the throat, including throat swabs and measuring the temperature.

All patients will then have their notes assessed to see whether they needed to come back to the GP/nurse or whether any complications occurred.

All patients are asked to complete a diary of their symptoms. The analysis will then assess whether the results of the throat swab are helpful in identifying those patients who are likely to benefit from antibiotics.

This information in turn can then be used to help doctors and nurse to better manage patients presenting with sore throat in future.
 
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